Infection And Immunity a Text book of Immunology And Serology for Students And

ection on the Wassermann reaction has been almost entirely rewritten. Attention has been directed to the manner in which the danger from anaphylactic shock during serum treatment may be reduced to a minimum. Emphasis has been given to the important observation of Schick and his collaborators, that it is possible through the aid of an allergic skin reaction to recognize those individuals, whose blood normally contains a quantity of diphtheria antitoxin sufficient for purposes of protection. The same is true of the observation of Ashhurst and John, that by suitable technique more encouraging results may be obtained in the treatment of tetanus, after symptoms of the disease have once developed, than heretofore. The possibility has been pointed out that by means of vaccine treatment, , Hodgkin3s disease may be advantageously influenced, etc. In addition a bibliography has been introduced in which the student who may be interested in the historical development of the subject or in the details of modern immunological research, will find gathered together the more important references. For obvious reasons this collection is in no sense complete, and practically represents those papers. upon a study of which the volume as a whole is based. I would emphasize again that Infectionand Imm lnity was originally written as an. introduction to this most intricate subject, and to serve as a guide to further reading. So many details of technique, however, have since been added, that the book might now serve as a basis for a course of systematic instruction in Immunology in our medical schools, which could suitab1-be combinet1 n-it11 the u3ual course ill Cli iical Iat1iolog-of the third -ear. The author liopes that some of llis colleagues m r-see tlicir -ay clear to attempt such an inno-ation, ant1 also that the present ctlition will be accordecl the sarrle generous rreccption IIJ-tlie general practitioner, for n-honl tlie booli was prinlari1-concei ed, as its predecessors. .. E. S. CONTENTS C H A P T E R I Immunology . . . . . . . . . . . . . . . . . 19 Infection and Infectious Diseases . . . . . . . . . . . . 20 Bibliography . . . . . . . . . . . . . . . 22 C H A P T E R I 1 Local Conditions and Infection . . . . . . . . . . . . . 23 Obstacles to Infection . . . . . . . . . . . . . . . . 25 Bibliography . . . . . . . . . . . . . . . . . . 28 C H A P T E R I11 Classification of Rlicroparasites . . . . . . . . . . . . . 29 Virulence and Aggressivit . . . . . . . . . . . . . . 32 Aggressins . . . . . . . . . . . . . . . . . . 35 PassiveAggresivity . . . . . . . . . . . . . . . 35 Active Aggresivit . . . . . . . . . . . . . . . . . 42 Bibliography . . . . . . . . . . . . . . . . . 46 C H A P T E R I V Ptomains . . . . . . . . . . . . . . . . . . ...